Genetic Counselling and Epilepsy: Understanding the Risks for Future Generations – News18

Last Updated:February 17, 2025, 12:24 IST

Genetic counseling helps families grasp their individual risk and equips them with the information needed to make informed decisions

Genetic counselling is a process where trained professionals assist individuals and families in understanding the medical, psychological, and familial implications of genetic conditions. It plays a significant role in understanding the hereditary aspects of various health disorders, including epilepsy. As a neurological condition, characterized by recurrent seizures, Epilepsy can sometimes have a genetic link, raising concerns for individuals with a family history of the disorder.

For individuals suffering from epilepsy, genetic counselling provides an opportunity to evaluate the risks of passing the condition on to future generations. By examining genetic factors, inheritance patterns, and the latest research, genetic counsellors empower individuals to make informed decisions about family planning and better manage the potential risks associated with epilepsy. Dr Sai Manasa Darla, Clinical Head & Fertility Specialist, Oasis Fertility explores the role of genetic counselling in epilepsy, highlighting how it helps individuals and families understand the risks and take proactive steps to ensure healthier futures.

While epilepsy has a genetic component, it’s important to note that not all forms of epilepsy are inherited. Epileptic seizures can be caused by single-gene disorders, such as Dravet syndrome or Tuberous Sclerosis, or by more complex genetic variations that increase susceptibility to seizures. Genetic testing can sometimes identify specific genes involved, offering clarity on the inheritance pattern and the likelihood of recurrence in future generations.

Understanding the inheritance pattern is key to managing risks. Some genetic epilepsies follow Mendelian inheritance patterns (dominant, recessive, or X-linked), while others are influenced by a combination of multiple genes and environmental factors. A genetic counselor helps families navigate these patterns, making complex medical information accessible and understandable.

For families with a history of epilepsy, genetic counseling can offer valuable support, including:

1. Assessing the recurrence risk: Determining the likelihood of passing the condition to future children.
2. Guiding family planning: Providing information that aids in making informed decisions about having children.
3. Offering genetic testing: Discussing the availability and impact of genetic testing.
4. Connecting with resources: Linking families to support groups and relevant information for further assistance.It’s essential to understand that while genetic predisposition can increase the likelihood of developing epilepsy, not everyone with a family history will experience the condition. Environmental factors can also contribute to the development of epilepsy. Genetic counseling helps families grasp their individual risk and equips them with the information needed to make informed decisions. If you or your family have a history of epilepsy, consulting a genetic counsellor can help you understand the genetic implications and manage the risks associated with future fertility and family planning.